Ne responses; highly immunogenicity in human stable; easy storage and transportNe responses; highly immunogenicity in human stable; easy storage and transport; compared to mice; low large-scale production; optimization transfection efficiency of plasmids and transcript is possibleActivation of antigen-specific B cells, CD4+ and CD8+ T cellsVectored vaccinesNanoparticlesLive recombinant Abili

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Ficient RNA replication resulting in almost 200000 RNA copies [27] from each RNAFicient RNA replication resulting in almost 200000 RNA copies [27] from each RNA template . Although replication-deficient particles provide a high level of safety, there is still a marginal risk of the generation of replication-proficient particles through nonhomologous recombination. To minimize this risk, spli

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Luble/secreted plasmid product may simultaneously gain access to the majorLuble/secreted plasmid product may simultaneously gain access to the major histocompatibility complex (MHC) class II exogenous pathway in phagocytic cells, for the [15] activation of B cells, CD4+ and CD8+ T lymphocytes . Many reports emphasized on the ability of DNA vaccines to induce immune responses against a variet

Luble/secreted plasmid product may simultaneously gain access to the majorLuble/secreted plasmid product may simultaneously gain access to the major histocompatibility complex (MHC) class II exogenous pathway in phagocytic cells, for the [15] activation of B cells, CD4+ and CD8+ T lymphocytes . Many reports emphasized on the ability of DNA vaccines to induce immune responses against a variet

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